The blood-tumor barrier (BTB) restricts the efficient delivery of anti-glioma drugs to cranial glioma tissues.Increased BTB permeability may allow greater delivery of the therapeutic agents.Increasing evidence has revealed that PIWI proteins and PIWI-interacting RNAs (piRNAs) play an important role in tumor progression.However, whether PIWI protein
Abstract Acupuncture is an alternative treatment for wide spectrum chronic pain.However, its validity remains controversial due to the disputed efficacy assessed in various clinical studies.Moreover, variability amongst individuals complicates the predictability of outcome, which impedes the integration of acupuncture into mainstream pain managemen
Abstract Background Tomato, Solanum lycopersicum L.(Solanales: Solanaceae) is the second most important vegetable crop in Egypt and is infested with many insect pests.The cotton leafworm, Spodoptera littoralis (Boisd.) causes severe economic losses in tomatoes and many other crops.Many management strategies were developed in order to manage the eco
In this paper, the aging resistance of sandwich structures made with cork agglomerate as core and flax-reinforced polymeric laminates as face sheets was investigated for the first time.In order hand wipes individual packets to evaluate their durability in a hostile environment, a sandwich plate was manufactured by vacuum bagging technique and aged
In this paper, a multi-item inventory model with space constraint is developed in both crisp and fuzzy environment.A profit maximization inventory model is proposed here to determine the optimal values of demands and order levels of a product.Selling price and unit price are new balance 990 v3 red assumed to be demand-dependent and holding and set-